Hydrogen-rich saline protects against ultraviolet B radiation injury in rats

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Hydrogen-rich saline protects against ultraviolet B radiation injury in rats

Exposure of skin to solar ultraviolet (UV) radiation induces photo-damage. Ultraviolet B (UVB) is the major component of UV radiation which induces the production of reactive oxygen species (ROS) and plays an important role in photo-damage. Hydrogen gas reduces ROS and alleviates inflammation. In this study, we sought to demonstrate that hydrogen-rich saline has the effect on skin injuries caus...

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Hydrogen-rich saline protects myocardium against ischemia/reperfusion injury in rats.

Protective effect of hydrogen (H(2)) gas on cardiac ischemia-reperfusion (I/R) injury has been demonstrated previously. This study was designed to test the hypothesis that hydrogen-rich saline (saline saturated with molecular hydrogen), which is easy to use, induces cardioprotection against ischemia (30 min) and reperfusion (24 h) injury in rats. Adult male Sprague-Dawley rats underwent 30-min ...

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Hydrogen-rich saline protects against liver injury in rats with obstructive jaundice.

BACKGROUND Hydrogen selectively reduces levels of hydroxyl radicals and alleviates acute oxidative stress in many models. Hydrogen-rich saline provides a high concentration of hydrogen that can be easily and safely applied. AIMS In this study, we investigated the effects of hydrogen-rich saline on the prevention of liver injury induced by obstructive jaundice in rats. METHODS Male Sprague-D...

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Hydrogen-rich saline protects against intestinal ischemia/reperfusion injury in rats.

Hydrogen gas was reported to reduce reactive oxygen species and alleviate cerebral, myocardial and hepatic ischemia/reperfusion (I/R) injuries. This paper studied the effect of hydrogen-rich saline, which was easier for clinical application, on the intestinal I/R injury. Model of intestinal I/R injury was induced in male Sprague-Dawley rats. Physiological saline, hydrogen-rich saline or nitroge...

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Hydrogen-rich saline protects immunocytes from radiation-induced apoptosis

BACKGROUND Radiation often causes depletion of immunocytes in tissues and blood, which results in immunosuppression. Molecular hydrogen (H2) has been shown in recent studies to have potential as a safe and effective radioprotective agent through scavenging free radicals. This study was designed to test the hypothesis that H2 could protect immunocytes from ionizing radiation (IR). MATERIAL/MET...

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ژورنال

عنوان ژورنال: Journal of Biomedical Research

سال: 2012

ISSN: 1674-8301

DOI: 10.7555/jbr.26.20110037